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2022-12-06

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2022-12-04

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2022-12-04

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2022-11-29

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Sidedi applies to issue 16.35 million shares through Hong Kong IPO

2022-11-29

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2022-11-29

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"New Stock News" 3D MEDICINES-B (01244. HK) will launch an IPO today, with a first-hand admission fee of 13,252.23 yuan

2022-11-29

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Sorry, the original content has been removed

2022-11-29

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New Stock Offering | 3D MEDICINES-B offers IPO today, admission fee is HK $13,252.23

2022-11-22

Woow going cool🔥😀

2022-11-22

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@木讷呆滞的短线价格投机:NQ100的首位度，越來越分化了，但只要一哥二哥穩如老狗，就問題不大！

2022-11-16

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@AdaMao:$3B家居(BBBY)$ 想問下大家，這玩意還有救嗎？我在山頂入的，現在就剩一條破褲衩了，還有必要留着嗎？

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The stock issue price guidance range is HK $22.96-26.24 per share. Trading is expected to begin on December 15.</p><p></body></html></p>\n<div class=\"bt-text\">\n\n\n<p> source：<a href=\"https://cj.sina.cn/article/normal_detail?url=https://finance.sina.com.cn/7x24/2022-11-29/doc-imqmmthc6355254.shtml\">媒体滚动</a></p>\n\n\n</div>\n</article>\n</div>\n</body>\n</html>\n","type":0,"thumbnail":"","relate_stocks":{"01244":"思路迪医药股份","IPO":"Renaissance IPO ETF"},"source_url":"https://cj.sina.cn/article/normal_detail?url=https://finance.sina.com.cn/7x24/2022-11-29/doc-imqmmthc6355254.shtml","is_english":false,"share_image_url":"https://static.laohu8.com/e9f99090a1c2ed51c021029395664489","article_id":"2287354144","content_text":"思路迪（3D Medicines）在港交所公告称，申请通过香港IPO发行1635万股股票，股票发行价指导区间为每股22.96-26.24港元，预计12月15日将开始交易。","news_type":1,"symbols_score_info":{"01244":1,"IPO":1}},"isVote":1,"tweetType":1,"viewCount":2096,"authorTweetTopStatus":1,"verified":2,"comments":[],"imageCount":0,"langContent":"EN","totalScore":0},{"id":620870264,"gmtCreate":1669690966159,"gmtModify":1676538224024,"author":{"id":"4130472326487360","authorId":"4130472326487360","name":"6f1a6f45","avatar":"https://static.laohu8.com/default-avatar.jpg","crmLevel":11,"crmLevelSwitch":0,"followedFlag":false,"authorIdStr":"4130472326487360","idStr":"4130472326487360"},"themes":[],"htmlText":"👍","listText":"👍","text":"👍","images":[],"top":1,"highlighted":1,"essential":1,"paper":1,"likeSize":0,"commentSize":0,"repostSize":0,"link":"https://ttm.financial/post/620870264","repostId":"2287453885","repostType":2,"isVote":1,"tweetType":1,"viewCount":1937,"authorTweetTopStatus":1,"verified":2,"comments":[],"imageCount":0,"langContent":"EN","totalScore":0},{"id":620870130,"gmtCreate":1669690916322,"gmtModify":1676538224016,"author":{"id":"4130472326487360","authorId":"4130472326487360","name":"6f1a6f45","avatar":"https://static.laohu8.com/default-avatar.jpg","crmLevel":11,"crmLevelSwitch":0,"followedFlag":false,"authorIdStr":"4130472326487360","idStr":"4130472326487360"},"themes":[],"htmlText":"👍","listText":"👍","text":"👍","images":[],"top":1,"highlighted":1,"essential":1,"paper":1,"likeSize":0,"commentSize":0,"repostSize":0,"link":"https://ttm.financial/post/620870130","repostId":"2287545465","repostType":2,"repost":{"id":"2287545465","kind":"news","pubTimestamp":1669681671,"share":"https://ttm.financial/m/news/2287545465?lang=en_US&edition=fundamental","pubTime":"2022-11-29 08:27","market":"us","language":"zh","title":"\"New Stock News\" 3D MEDICINES-B (01244. HK) will launch an IPO today, with a first-hand admission fee of 13,252.23 yuan","url":"https://stock-news.laohu8.com/highlight/detail?id=2287545465","media":"AAFN","summary":"生物医药公司3D MEDICINES-B公布招股详情，拟全球发售1,635万股，香港公开发售占一成，国际发售占九成。招股价介乎每股22.96至26.24元。每手500股计，一手入场费13,252.23元。该股今日起招股，下周三中午截止，预期将于12月15日挂牌。公司上市引入4名基石投资者，包括徐州经开区(香港)、Harvest、TradArt Investment SP及Mobilewise，合共认购2.35亿元公司股份。","content":"<p><html><body>The biopharmaceutical company 3D MEDICINES-B (01244. HK) announced the details of its IPO. It plans to sell 16.35 million shares globally, with Hong Kong public offering accounting for 10% and international offering accounting for 90%. The offering price ranges from 22.96 to 26.24 yuan per share. Each lot is 500 shares, and the admission fee for one lot is 13,252.23 yuan. The stock will be launched today (November 29th) and will close at noon next Wednesday (December 7th). It is expected to be listed on December 15th. The joint sponsors are CICC and<a href=\"https://laohu8.com/S/601066\">China Securities Investment</a>International. The company's listing introduced 4 cornerstone investors, including Xuzhou Economic Development Zone (Hong Kong), Harvest, TradArt Investment SP and Mobilewise, who subscribed for a total of 235 million yuan of company shares. For example, based on the median offering price of 24.6 yuan, the company's listing is expected to raise a net fund of about 245 million yuan, of which about 90% is mainly used for the research and development, regulatory filing and commercialization of products and drug candidates; About 10% will be used for general corporate and working capital purposes. (jl/w) ~ Aastock Financial News Website: www.aastocks.com</p><p></body></html></p>","source":"aastocks","collect":0,"html":"<!DOCTYPE html>\n<html>\n<head>\n<meta http-equiv=\"Content-Type\" content=\"text/html; charset=utf-8\" />\n<meta name=\"viewport\" content=\"width=device-width,initial-scale=1.0,minimum-scale=1.0,maximum-scale=1.0,user-scalable=no\"/>\n<meta name=\"format-detection\" content=\"telephone=no,email=no,address=no\" />\n<title>\"New Stock News\" 3D MEDICINES-B (01244. HK) will launch an IPO today, with a first-hand admission fee of 13,252.23 yuan</title>\n<style type=\"text/css\">\na,abbr,acronym,address,applet,article,aside,audio,b,big,blockquote,body,canvas,caption,center,cite,code,dd,del,details,dfn,div,dl,dt,\nem,embed,fieldset,figcaption,figure,footer,form,h1,h2,h3,h4,h5,h6,header,hgroup,html,i,iframe,img,ins,kbd,label,legend,li,mark,menu,nav,\nobject,ol,output,p,pre,q,ruby,s,samp,section,small,span,strike,strong,sub,summary,sup,table,tbody,td,tfoot,th,thead,time,tr,tt,u,ul,var,video{ font:inherit;margin:0;padding:0;vertical-align:baseline;border:0 }\nbody{ font-size:16px; line-height:1.5; color:#999; background:transparent; }\n.wrapper{ overflow:hidden;word-break:break-all;padding:10px; }\nh1,h2{ font-weight:normal; line-height:1.35; margin-bottom:.6em; }\nh3,h4,h5,h6{ line-height:1.35; margin-bottom:1em; }\nh1{ font-size:24px; }\nh2{ font-size:20px; }\nh3{ font-size:18px; }\nh4{ font-size:16px; }\nh5{ font-size:14px; }\nh6{ font-size:12px; }\np,ul,ol,blockquote,dl,table{ margin:1.2em 0; }\nul,ol{ margin-left:2em; }\nul{ list-style:disc; }\nol{ list-style:decimal; }\nli,li p{ margin:10px 0;}\nimg{ max-width:100%;display:block;margin:0 auto 1em; }\nblockquote{ color:#B5B2B1; border-left:3px solid #aaa; padding:1em; }\nstrong,b{font-weight:bold;}\nem,i{font-style:italic;}\ntable{ width:100%;border-collapse:collapse;border-spacing:1px;margin:1em 0;font-size:.9em; }\nth,td{ padding:5px;text-align:left;border:1px solid #aaa; }\nth{ font-weight:bold;background:#5d5d5d; }\n.symbol-link{font-weight:bold;}\n/* header{ border-bottom:1px solid #494756; } */\n.title{ margin:0 0 8px;line-height:1.3;color:#ddd; }\n.meta {color:#5e5c6d;font-size:13px;margin:0 0 .5em; }\na{text-decoration:none; color:#2a4b87;}\n.meta .head { display: inline-block; overflow: hidden}\n.head .h-thumb { width: 30px; height: 30px; margin: 0; padding: 0; border-radius: 50%; float: left;}\n.head .h-content { margin: 0; padding: 0 0 0 9px; float: left;}\n.head .h-name {font-size: 13px; color: #eee; margin: 0;}\n.head .h-time {font-size: 12.5px; color: #7E829C; margin: 0;}\n.small {font-size: 12.5px; display: inline-block; transform: scale(0.9); -webkit-transform: scale(0.9); transform-origin: left; -webkit-transform-origin: left;}\n.smaller {font-size: 12.5px; display: inline-block; transform: scale(0.8); -webkit-transform: scale(0.8); transform-origin: left; -webkit-transform-origin: left;}\n.bt-text {font-size: 12px;margin: 1.5em 0 0 0}\n.bt-text p {margin: 0}\n</style>\n</head>\n<body>\n<div class=\"wrapper\">\n<header>\n<h2 class=\"title\">\n\"New Stock News\" 3D MEDICINES-B (01244. HK) will launch an IPO today, with a first-hand admission fee of 13,252.23 yuan\n</h2>\n<h4 class=\"meta\">\n<p class=\"head\">\n<strong class=\"h-name small\">AAFN</strong><span class=\"h-time small\">2022-11-29 08:27</span>\n</p>\n</h4>\n</header>\n<article>\n<p><html><body>The biopharmaceutical company 3D MEDICINES-B (01244. HK) announced the details of its IPO. It plans to sell 16.35 million shares globally, with Hong Kong public offering accounting for 10% and international offering accounting for 90%. The offering price ranges from 22.96 to 26.24 yuan per share. Each lot is 500 shares, and the admission fee for one lot is 13,252.23 yuan. The stock will be launched today (November 29th) and will close at noon next Wednesday (December 7th). It is expected to be listed on December 15th. The joint sponsors are CICC and<a href=\"https://laohu8.com/S/601066\">China Securities Investment</a>International. The company's listing introduced 4 cornerstone investors, including Xuzhou Economic Development Zone (Hong Kong), Harvest, TradArt Investment SP and Mobilewise, who subscribed for a total of 235 million yuan of company shares. For example, based on the median offering price of 24.6 yuan, the company's listing is expected to raise a net fund of about 245 million yuan, of which about 90% is mainly used for the research and development, regulatory filing and commercialization of products and drug candidates; About 10% will be used for general corporate and working capital purposes. (jl/w) ~ Aastock Financial News Website: www.aastocks.com</p><p></body></html></p>\n<div class=\"bt-text\">\n\n\n<p> source：<a href=\"http://www.aastocks.com/apps/data/iphone/news/newscontent.aspx?newsid=NOW.1229684&style=5&chgstyle=1&categoryid=stock&width=320&market_id=hk&fontary=3&platform=iPhone&language=sc&isfirstreq=1&sourceid=aafn&datatype=0\">AAFN</a></p>\n\n\n</div>\n</article>\n</div>\n</body>\n</html>\n","type":0,"thumbnail":"","relate_stocks":{"LU0140636845.USD":"施罗德大中华区股票A Acc","LU0251144936.SGD":"Fidelity Sustainable Asia Equity A-SGD","LU0067412154.USD":"UBS (LUX) EQUITY FUND -  CHINA OPPORTUNITY \"P\" (USD) ACC","LU0501845795.SGD":"瑞银大中华区股票基金P Acc SGD","LU0043850808.USD":"HSBC GIF ASIA EX JAPAN EQUITY \"AD\" INC","LU0873338254.USD":"FULLERTON LUX FUNDS - ASIA GROWTH & INCOME EQUITIE \"I\" (USD) INC","LU0577902538.SGD":"Fullerton Lux Funds - Asia Growth and Income Equities A Acc SGD","BK1589":"北水核心资产","BK1521":"挪威政府全球养老基金持仓","LU0417516738.SGD":"Allianz Hong Kong Equity AT Acc SGD","LU0348735423.USD":"ALLIANZ HONG KONG EQUITY \"A\" (USD) INC","LU0577902611.USD":"FULLERTON LUX FUNDS - ASIA GROWTH & INCOME EQUITIE \"A\" (USD) ACC","SG9999004220.SGD":"Nikko AM Shenton Asia Dividend Equity Fund  SGD","LU0577902454.USD":"FULLERTON LUX FUNDS - ASIA GROWTH & INCOME EQUITIE \"I\" (USD) ACC","LU0577902371.SGD":"FULLERTON LUX FUNDS - ASIA GROWTH & INCOME EQUITIE \"I\" (SGD) ACC","BK1131":"金融交易所和数据","LU0456846285.SGD":"JPMorgan Funds - Greater China A (acc) SGD","01244":"思路迪医药股份","LU1044876610.USD":"THREADNEEDLE (LUX) ASIAN CONTRARIAN EQUITY \"ZU\" (USD) ACC","SG9999002463.SGD":"LionGlobal China Growth SGD","LU0072913022.USD":"UBS (LUX) EQUITY FUND -  GREATER CHINA \"P\" (USD) ACC","LU0048597586.USD":"富达亚洲焦点A","LU0572944931.SGD":"Janus Henderson Horizon China Opportunities A2 SGD","LU1226287529.USD":"UBS (LUX) KEY SELECTION SICAV - CHINA ALLOCATION  OPPORTUNITY (USD) \"P\" (USD) ACC","LU1642822792.SGD":"THREADNEEDLE (LUX) ASIAN CONTRARIAN EQUITY \"A\" (SGD) ACC","00388":"香港交易所","LU1044874839.SGD":"THREADNEEDLE (LUX) ASIAN CONTRARIAN EQUITY \"AGH\" (SGDHDG) ACC","LU0211977185.USD":"EASTSPRING INVESTMENTS GREATER CHINA EQUITY \"A\" ACC","LU2039709279.SGD":"MANULIFE GF DRAGON GROWTH \"AA\" (SGDHDG) INC","LU1044875133.USD":"天利亚洲反向股票 AU Acc","LU0327786744.USD":"Janus Henderson Horizon China Opportunities A2 USD","LU1807302812.USD":"UBS (LUX) EQUITY SICAV ALL CHINA \"P\" (USD) ACC","LU0577902298.EUR":"FULLERTON LUX FUNDS - ASIA GROWTH & INCOME EQUITIE \"I\" (EUR) ACC"},"source_url":"http://www.aastocks.com/apps/data/iphone/news/newscontent.aspx?newsid=NOW.1229684&style=5&chgstyle=1&categoryid=stock&width=320&market_id=hk&fontary=3&platform=iPhone&language=sc&isfirstreq=1&sourceid=aafn&datatype=0","is_english":false,"share_image_url":"https://static.laohu8.com/51f6b9126f36f92bbf92982596066e5a","article_id":"2287545465","content_text":"生物医药公司3D MEDICINES-B(01244.HK)公布招股详情，拟全球发售1,635万股，香港公开发售占一成，国际发售占九成。招股价介乎每股22.96至26.24元。每手500股计，一手入场费13,252.23元。该股今日(11月29日)起招股，下周三(12月7日)中午截止，预期将于12月15日挂牌。联席保荐人为中金及中信建投国际。公司上市引入4名基石投资者，包括徐州经开区(香港)、Harvest、TradArt Investment SP及Mobilewise，合共认购2.35亿元公司股份。如以招股价中位数24.6元计，公司上市料净集资约2.45亿元，当中约90%主要用于产品和候选药物的研发、监管备案及商业化；约10%将用于一般企业及营运资金用途。(jl/w)~阿思达克财经新闻网址: www.aastocks.com","news_type":1,"symbols_score_info":{"00388":0.9,"01244":1}},"isVote":1,"tweetType":1,"viewCount":1797,"authorTweetTopStatus":1,"verified":2,"comments":[],"imageCount":0,"langContent":"EN","totalScore":0},{"id":620870046,"gmtCreate":1669690798187,"gmtModify":1676538224000,"author":{"id":"4130472326487360","authorId":"4130472326487360","name":"6f1a6f45","avatar":"https://static.laohu8.com/default-avatar.jpg","crmLevel":11,"crmLevelSwitch":0,"followedFlag":false,"authorIdStr":"4130472326487360","idStr":"4130472326487360"},"themes":[],"htmlText":"👍","listText":"👍","text":"👍","images":[],"top":1,"highlighted":1,"essential":1,"paper":1,"likeSize":0,"commentSize":0,"repostSize":0,"link":"https://ttm.financial/post/620870046","repostId":"2287254564","repostType":2,"isVote":1,"tweetType":1,"viewCount":2380,"authorTweetTopStatus":1,"verified":2,"comments":[],"imageCount":0,"langContent":"EN","totalScore":0},{"id":620847528,"gmtCreate":1669690625866,"gmtModify":1676538223984,"author":{"id":"4130472326487360","authorId":"4130472326487360","name":"6f1a6f45","avatar":"https://static.laohu8.com/default-avatar.jpg","crmLevel":11,"crmLevelSwitch":0,"followedFlag":false,"authorIdStr":"4130472326487360","idStr":"4130472326487360"},"themes":[],"htmlText":"👍","listText":"👍","text":"👍","images":[],"top":1,"highlighted":1,"essential":1,"paper":1,"likeSize":0,"commentSize":0,"repostSize":0,"link":"https://ttm.financial/post/620847528","repostId":"1107729224","repostType":2,"repost":{"id":"1107729224","kind":"news","weMediaInfo":{"introduction":"为用户提供金融资讯、行情、数据，旨在帮助投资者理解世界，做投资决策。","home_visible":1,"media_name":"老虎资讯综合","id":"102","head_image":"https://static.tigerbbs.com/8274c5b9d4c2852bfb1c4d6ce16c68ba"},"pubTimestamp":1669684496,"share":"https://ttm.financial/m/news/1107729224?lang=en_US&edition=fundamental","pubTime":"2022-11-29 09:14","market":"hk","language":"zh","title":"New Stock Offering | 3D MEDICINES-B offers IPO today, admission fee is HK $13,252.23","url":"https://stock-news.laohu8.com/highlight/detail?id=1107729224","media":"老虎资讯综合","summary":"11月29日，3D MEDICINES-B发布公告，公司拟全球发售1635万股股份，其中中国香港发售股份163.5万股，国际发售股份1471.5万股，另有15%超额配股权；2022年11月29日至12","content":"<p><html><head></head><body>November 29th,<a href=\"https://laohu8.com/S/01244\">3D MEDICINES-B</a>Announced that the company plans to sell 16.35 million shares globally, including 1.635 million shares offered in Hong Kong, China, 14.715 million shares offered internationally, and a 15% over-allotment option; The IPO will be held from November 29 to December 7, 2022, and the expected pricing date is December 7; The offer price will be HK $22.96-26.24 per offer share, with 500 shares per lot, and the admission fee will be approximately HK $13,252.23; CICC and China Securities International are joint sponsors; It is expected that the Shares will be listed on the Main Board of the Stock Exchange on 15 December 2022.</p><p><img src=\"https://static.tigerbbs.com/2c0be958a118bf20d9cd87db8c523bd9\" tg-width=\"897\" tg-height=\"709\" width=\"100%\" height=\"auto\"/></p><p><b>Subscription ladder:</b></p><p>There are 500 shares per lot, and the admission fee is HK $13,252.23.</p><p>The threshold for Group B is 2 million shares, and the funds required for subscription are approximately HK $5,300,891.97.</p><p><img src=\"https://static.tigerbbs.com/c92f15f2d5dc92f088705e284d6c494f\" tg-width=\"897\" tg-height=\"535\" width=\"100%\" height=\"auto\"/></p><p>The Group is a biomedical company founded in 2014, dedicated to the development of oncology drugs for cancer patients, especially those who need long-term treatment. The Group's core business model is to develop and commercialize oncology products and drug candidates through joint cooperation development, licensing introduction and independent discovery. The Group plans to further enhance the Group's internal discovery capabilities after listing and continue to use the cooperative development and licensing introduction model to carry out clinical trials for more indications for the benefit of chronic cancer patients. As of the Latest Practicable Date, the Group has established a pipeline consisting of one core product and 11 drug candidates, of which the core product envolimab (brand name: Envida ® ) is the pillar product of the Group, which has been approved in November 2021 and commercialized in December 2021, and seven other drug candidates are in the clinical stage (including that the Group has initiated clinical trials or has obtained IND approval and is preparing to initiate clinical trial drug candidates).</p><p>The Group's core product, envolimab, is a subcutaneous PD-L1 antibody, which has been approved in China for the treatment of previously treated microsatellite high instability (MSI-H)/mismatch repair function defect (dMMR) advanced solid tumors. As of the Latest Practicable Date, the Group's core products were only approved for this indication. According to Frost & Sullivan, as of the Latest Practicable Date, there were four commercial peers and five clinical-stage peers competing with the Core Products in China for the treatment of MSI-H/dMMR tumors. The Group faces fierce competition from existing products and potential drug candidates (including monoclonal and bispecific antibodies targeting PD-1/L1) in the overall oncology market. The market opportunity for core products may be small because it targets most Late-stage treatment of target indications. For example, the incidence of MSI-H/dMMR advanced solid tumors in China was approximately 146,100 cases in 2021 and is expected to reach approximately 186,000 cases in 2030, and only approximately 50% of cases will receive more than one treatment.</p><p>The Group has entered into a cornerstone investment agreement, pursuant to which the cornerstone investors have agreed to subscribe for an aggregate of HK $235 million in Offer Shares at the Offer Price subject to certain conditions. Assuming an Offer Price of HK $24.60 (i.e. the mid-point of the indicative Offer Price range set out in this prospectus), the total number of Offer Shares to be subscribed for by cornerstone investors is 9,536,500 Offer Shares. Cornerstone investors include Xuzhou Economic and Technological Development Zone (Hong Kong) Investment Co., Ltd., Harvest, TradArt Investment SP, and Mobilewise.</p><p><img src=\"https://static.tigerbbs.com/65b7af483bb5bb129e17cb7a66844666\" tg-width=\"894\" tg-height=\"522\" width=\"100%\" height=\"auto\"/></p><p>Assuming that the over-allotment option is not exercised and the offer price is HK $24.60 per share, the Group estimates that the total net proceeds from the global offering that the company will receive will be approximately HK $245 million. The Group currently plans to use approximately 90% of the net proceeds that the Group will receive from this offering mainly for the research and development, regulatory filing and commercialization of the Group's products and drug candidates; And approximately 10% will be used for the group's general corporate and working capital purposes.</p><p></body></html></p>","collect":0,"html":"<!DOCTYPE html>\n<html>\n<head>\n<meta http-equiv=\"Content-Type\" content=\"text/html; charset=utf-8\" />\n<meta name=\"viewport\" content=\"width=device-width,initial-scale=1.0,minimum-scale=1.0,maximum-scale=1.0,user-scalable=no\"/>\n<meta name=\"format-detection\" content=\"telephone=no,email=no,address=no\" />\n<title>New Stock Offering | 3D MEDICINES-B offers IPO today, admission fee is HK $13,252.23</title>\n<style type=\"text/css\">\na,abbr,acronym,address,applet,article,aside,audio,b,big,blockquote,body,canvas,caption,center,cite,code,dd,del,details,dfn,div,dl,dt,\nem,embed,fieldset,figcaption,figure,footer,form,h1,h2,h3,h4,h5,h6,header,hgroup,html,i,iframe,img,ins,kbd,label,legend,li,mark,menu,nav,\nobject,ol,output,p,pre,q,ruby,s,samp,section,small,span,strike,strong,sub,summary,sup,table,tbody,td,tfoot,th,thead,time,tr,tt,u,ul,var,video{ font:inherit;margin:0;padding:0;vertical-align:baseline;border:0 }\nbody{ font-size:16px; line-height:1.5; color:#999; background:transparent; }\n.wrapper{ overflow:hidden;word-break:break-all;padding:10px; }\nh1,h2{ font-weight:normal; line-height:1.35; margin-bottom:.6em; }\nh3,h4,h5,h6{ line-height:1.35; margin-bottom:1em; }\nh1{ font-size:24px; }\nh2{ font-size:20px; }\nh3{ font-size:18px; }\nh4{ font-size:16px; }\nh5{ font-size:14px; }\nh6{ font-size:12px; }\np,ul,ol,blockquote,dl,table{ margin:1.2em 0; }\nul,ol{ margin-left:2em; }\nul{ list-style:disc; }\nol{ list-style:decimal; }\nli,li p{ margin:10px 0;}\nimg{ max-width:100%;display:block;margin:0 auto 1em; }\nblockquote{ color:#B5B2B1; border-left:3px solid #aaa; padding:1em; }\nstrong,b{font-weight:bold;}\nem,i{font-style:italic;}\ntable{ width:100%;border-collapse:collapse;border-spacing:1px;margin:1em 0;font-size:.9em; }\nth,td{ padding:5px;text-align:left;border:1px solid #aaa; }\nth{ font-weight:bold;background:#5d5d5d; }\n.symbol-link{font-weight:bold;}\n/* header{ border-bottom:1px solid #494756; } */\n.title{ margin:0 0 8px;line-height:1.3;color:#ddd; }\n.meta {color:#5e5c6d;font-size:13px;margin:0 0 .5em; }\na{text-decoration:none; color:#2a4b87;}\n.meta .head { display: inline-block; overflow: hidden}\n.head .h-thumb { width: 30px; height: 30px; margin: 0; padding: 0; border-radius: 50%; float: left;}\n.head .h-content { margin: 0; padding: 0 0 0 9px; float: left;}\n.head .h-name {font-size: 13px; color: #eee; margin: 0;}\n.head .h-time {font-size: 12.5px; color: #7E829C; margin: 0;}\n.small {font-size: 12.5px; display: inline-block; transform: scale(0.9); -webkit-transform: scale(0.9); transform-origin: left; -webkit-transform-origin: left;}\n.smaller {font-size: 12.5px; display: inline-block; transform: scale(0.8); -webkit-transform: scale(0.8); transform-origin: left; -webkit-transform-origin: left;}\n.bt-text {font-size: 12px;margin: 1.5em 0 0 0}\n.bt-text p {margin: 0}\n</style>\n</head>\n<body>\n<div class=\"wrapper\">\n<header>\n<h2 class=\"title\">\nNew Stock Offering | 3D MEDICINES-B offers IPO today, admission fee is HK $13,252.23\n</h2>\n<h4 class=\"meta\">\n<a class=\"head\" href=\"https://laohu8.com/wemedia/102\">\n\n<div class=\"h-thumb\" style=\"background-image:url(https://static.tigerbbs.com/8274c5b9d4c2852bfb1c4d6ce16c68ba);background-size:cover;\"></div>\n\n<div class=\"h-content\">\n<p class=\"h-name\">老虎资讯综合 </p>\n<p class=\"h-time smaller\">2022-11-29 09:14</p>\n</div>\n</a>\n</h4>\n</header>\n<article>\n<p><html><head></head><body>November 29th,<a href=\"https://laohu8.com/S/01244\">3D MEDICINES-B</a>Announced that the company plans to sell 16.35 million shares globally, including 1.635 million shares offered in Hong Kong, China, 14.715 million shares offered internationally, and a 15% over-allotment option; The IPO will be held from November 29 to December 7, 2022, and the expected pricing date is December 7; The offer price will be HK $22.96-26.24 per offer share, with 500 shares per lot, and the admission fee will be approximately HK $13,252.23; CICC and China Securities International are joint sponsors; It is expected that the Shares will be listed on the Main Board of the Stock Exchange on 15 December 2022.</p><p><img src=\"https://static.tigerbbs.com/2c0be958a118bf20d9cd87db8c523bd9\" tg-width=\"897\" tg-height=\"709\" width=\"100%\" height=\"auto\"/></p><p><b>Subscription ladder:</b></p><p>There are 500 shares per lot, and the admission fee is HK $13,252.23.</p><p>The threshold for Group B is 2 million shares, and the funds required for subscription are approximately HK $5,300,891.97.</p><p><img src=\"https://static.tigerbbs.com/c92f15f2d5dc92f088705e284d6c494f\" tg-width=\"897\" tg-height=\"535\" width=\"100%\" height=\"auto\"/></p><p>The Group is a biomedical company founded in 2014, dedicated to the development of oncology drugs for cancer patients, especially those who need long-term treatment. The Group's core business model is to develop and commercialize oncology products and drug candidates through joint cooperation development, licensing introduction and independent discovery. The Group plans to further enhance the Group's internal discovery capabilities after listing and continue to use the cooperative development and licensing introduction model to carry out clinical trials for more indications for the benefit of chronic cancer patients. As of the Latest Practicable Date, the Group has established a pipeline consisting of one core product and 11 drug candidates, of which the core product envolimab (brand name: Envida ® ) is the pillar product of the Group, which has been approved in November 2021 and commercialized in December 2021, and seven other drug candidates are in the clinical stage (including that the Group has initiated clinical trials or has obtained IND approval and is preparing to initiate clinical trial drug candidates).</p><p>The Group's core product, envolimab, is a subcutaneous PD-L1 antibody, which has been approved in China for the treatment of previously treated microsatellite high instability (MSI-H)/mismatch repair function defect (dMMR) advanced solid tumors. As of the Latest Practicable Date, the Group's core products were only approved for this indication. According to Frost & Sullivan, as of the Latest Practicable Date, there were four commercial peers and five clinical-stage peers competing with the Core Products in China for the treatment of MSI-H/dMMR tumors. The Group faces fierce competition from existing products and potential drug candidates (including monoclonal and bispecific antibodies targeting PD-1/L1) in the overall oncology market. The market opportunity for core products may be small because it targets most Late-stage treatment of target indications. For example, the incidence of MSI-H/dMMR advanced solid tumors in China was approximately 146,100 cases in 2021 and is expected to reach approximately 186,000 cases in 2030, and only approximately 50% of cases will receive more than one treatment.</p><p>The Group has entered into a cornerstone investment agreement, pursuant to which the cornerstone investors have agreed to subscribe for an aggregate of HK $235 million in Offer Shares at the Offer Price subject to certain conditions. Assuming an Offer Price of HK $24.60 (i.e. the mid-point of the indicative Offer Price range set out in this prospectus), the total number of Offer Shares to be subscribed for by cornerstone investors is 9,536,500 Offer Shares. Cornerstone investors include Xuzhou Economic and Technological Development Zone (Hong Kong) Investment Co., Ltd., Harvest, TradArt Investment SP, and Mobilewise.</p><p><img src=\"https://static.tigerbbs.com/65b7af483bb5bb129e17cb7a66844666\" tg-width=\"894\" tg-height=\"522\" width=\"100%\" height=\"auto\"/></p><p>Assuming that the over-allotment option is not exercised and the offer price is HK $24.60 per share, the Group estimates that the total net proceeds from the global offering that the company will receive will be approximately HK $245 million. The Group currently plans to use approximately 90% of the net proceeds that the Group will receive from this offering mainly for the research and development, regulatory filing and commercialization of the Group's products and drug candidates; And approximately 10% will be used for the group's general corporate and working capital purposes.</p><p></body></html></p>\n</article>\n</div>\n</body>\n</html>\n","type":0,"thumbnail":"https://static.tigerbbs.com/26d35a88c8d9d9d46abd395d2bd24396","relate_stocks":{"01244":"思路迪医药股份"},"source_url":"","is_english":false,"share_image_url":"https://static.laohu8.com/e9f99090a1c2ed51c021029395664489","article_id":"1107729224","content_text":"11月29日，3D MEDICINES-B发布公告，公司拟全球发售1635万股股份，其中中国香港发售股份163.5万股，国际发售股份1471.5万股，另有15%超额配股权；2022年11月29日至12月7日招股，预期定价日为12月7日；发售价将为每股发售股份22.96-26.24港元，每手买卖单位500股，入场费约13252.23港元；中金公司及中信建投国际为联席保荐人；预期股份将于2022年12月15日于联交所主板挂牌上市。申购阶梯：每手500股，入场费13252.23港元。乙组门槛为200000万股，申购所需资金约5300891.97港元。集团是一家成立于2014年的生物医药公司，致力于为癌症患者，尤其是那些需要长期治疗的患者研发肿瘤药物。集团的核心业务模式是通过联合合作开发、许可引进及自主发现等方式，开发及商业化肿瘤产品及候选药物。集团计划于上市后进一步提升集团的内部发现能力及继续利用合作开发及许可引进模式开展针对更多适应症的临床试验造福慢性癌症患者。截至最后实际可行日期，集团已建立一条包含一款核心产品及11款候选药物的管线，其中核心产品恩沃利单抗(品牌名：恩维达®)为集团的支柱产品，已于2021年11月获批并于2021年12月商业化，另有七款其他候选药物处于临床阶段(包括集团已启动临床试验或已取得IND批准及正准备启动临床试验的候选药物)。集团的核心产品恩沃利单抗是一款皮下注射PD-L1抗体，其已在中国获批用于治疗既往接受过治疗的微卫星高度不稳定(MSI-H)╱错配修复功能缺陷(dMMR)晚期实体瘤。截至最后实际可行日期，集团的核心产品仅获批用于这一适应症。根据弗若斯特沙利文的资料，截至最后实际可行日期，在中国有四名商业化同行及五名临床阶段同行就治疗MSI-H/dMMR肿瘤与核心产品竞争。集团于整个肿瘤市场面临来自现有产品及潜在候选药物(包括靶向PD-1/L1的单克隆及双特异性抗体)的激烈竞争，核心产品的市场机会可能很小，因为其靶向大多数目标适应症的晚期治疗。例如，MSI-H/ 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06:26","market":"us","language":"zh","title":"Sidedi applies to issue 16.35 million shares through Hong Kong IPO","url":"https://stock-news.laohu8.com/highlight/detail?id=2287354144","media":"媒体滚动","summary":"思路迪（3D Medicines）在港交所公告称，申请通过香港IPO发行1635万股股票，股票发行价指导区间为每股22.96-26.24港元，预计12月15日将开始交易。","content":"<p><html><body>3D Medicines announced on the Hong Kong Stock Exchange that it applied to issue 16.35 million shares through a Hong Kong IPO. The stock issue price guidance range is HK $22.96-26.24 per share. Trading is expected to begin on December 15.</p><p></body></html></p>","source":"sina_symbol","collect":0,"html":"<!DOCTYPE html>\n<html>\n<head>\n<meta http-equiv=\"Content-Type\" content=\"text/html; charset=utf-8\" />\n<meta name=\"viewport\" content=\"width=device-width,initial-scale=1.0,minimum-scale=1.0,maximum-scale=1.0,user-scalable=no\"/>\n<meta name=\"format-detection\" content=\"telephone=no,email=no,address=no\" />\n<title>Sidedi applies to issue 16.35 million shares through Hong Kong IPO</title>\n<style type=\"text/css\">\na,abbr,acronym,address,applet,article,aside,audio,b,big,blockquote,body,canvas,caption,center,cite,code,dd,del,details,dfn,div,dl,dt,\nem,embed,fieldset,figcaption,figure,footer,form,h1,h2,h3,h4,h5,h6,header,hgroup,html,i,iframe,img,ins,kbd,label,legend,li,mark,menu,nav,\nobject,ol,output,p,pre,q,ruby,s,samp,section,small,span,strike,strong,sub,summary,sup,table,tbody,td,tfoot,th,thead,time,tr,tt,u,ul,var,video{ font:inherit;margin:0;padding:0;vertical-align:baseline;border:0 }\nbody{ font-size:16px; line-height:1.5; color:#999; background:transparent; }\n.wrapper{ overflow:hidden;word-break:break-all;padding:10px; }\nh1,h2{ font-weight:normal; line-height:1.35; margin-bottom:.6em; }\nh3,h4,h5,h6{ line-height:1.35; margin-bottom:1em; }\nh1{ font-size:24px; }\nh2{ font-size:20px; }\nh3{ font-size:18px; }\nh4{ font-size:16px; }\nh5{ font-size:14px; }\nh6{ font-size:12px; }\np,ul,ol,blockquote,dl,table{ margin:1.2em 0; }\nul,ol{ margin-left:2em; }\nul{ list-style:disc; }\nol{ list-style:decimal; }\nli,li p{ margin:10px 0;}\nimg{ max-width:100%;display:block;margin:0 auto 1em; }\nblockquote{ color:#B5B2B1; border-left:3px solid #aaa; padding:1em; }\nstrong,b{font-weight:bold;}\nem,i{font-style:italic;}\ntable{ width:100%;border-collapse:collapse;border-spacing:1px;margin:1em 0;font-size:.9em; }\nth,td{ padding:5px;text-align:left;border:1px solid #aaa; }\nth{ font-weight:bold;background:#5d5d5d; }\n.symbol-link{font-weight:bold;}\n/* header{ border-bottom:1px solid #494756; } */\n.title{ margin:0 0 8px;line-height:1.3;color:#ddd; }\n.meta {color:#5e5c6d;font-size:13px;margin:0 0 .5em; }\na{text-decoration:none; color:#2a4b87;}\n.meta .head { display: inline-block; overflow: hidden}\n.head .h-thumb { width: 30px; height: 30px; margin: 0; padding: 0; border-radius: 50%; float: left;}\n.head .h-content { margin: 0; padding: 0 0 0 9px; float: left;}\n.head .h-name {font-size: 13px; color: #eee; margin: 0;}\n.head .h-time {font-size: 12.5px; color: #7E829C; margin: 0;}\n.small {font-size: 12.5px; display: inline-block; transform: scale(0.9); -webkit-transform: scale(0.9); transform-origin: left; -webkit-transform-origin: left;}\n.smaller {font-size: 12.5px; display: inline-block; transform: scale(0.8); -webkit-transform: scale(0.8); transform-origin: left; -webkit-transform-origin: left;}\n.bt-text {font-size: 12px;margin: 1.5em 0 0 0}\n.bt-text p {margin: 0}\n</style>\n</head>\n<body>\n<div class=\"wrapper\">\n<header>\n<h2 class=\"title\">\nSidedi applies to issue 16.35 million shares through Hong Kong IPO\n</h2>\n<h4 class=\"meta\">\n<p class=\"head\">\n<strong class=\"h-name small\">媒体滚动</strong><span class=\"h-time small\">2022-11-29 06:26</span>\n</p>\n</h4>\n</header>\n<article>\n<p><html><body>3D Medicines announced on the Hong Kong Stock Exchange that it applied to issue 16.35 million shares through a Hong Kong IPO. The stock issue price guidance range is HK $22.96-26.24 per share. Trading is expected to begin on December 15.</p><p></body></html></p>\n<div class=\"bt-text\">\n\n\n<p> source：<a href=\"https://cj.sina.cn/article/normal_detail?url=https://finance.sina.com.cn/7x24/2022-11-29/doc-imqmmthc6355254.shtml\">媒体滚动</a></p>\n\n\n</div>\n</article>\n</div>\n</body>\n</html>\n","type":0,"thumbnail":"","relate_stocks":{"01244":"思路迪医药股份","IPO":"Renaissance IPO ETF"},"source_url":"https://cj.sina.cn/article/normal_detail?url=https://finance.sina.com.cn/7x24/2022-11-29/doc-imqmmthc6355254.shtml","is_english":false,"share_image_url":"https://static.laohu8.com/e9f99090a1c2ed51c021029395664489","article_id":"2287354144","content_text":"思路迪（3D Medicines）在港交所公告称，申请通过香港IPO发行1635万股股票，股票发行价指导区间为每股22.96-26.24港元，预计12月15日将开始交易。","news_type":1,"symbols_score_info":{"01244":1,"IPO":1}},"isVote":1,"tweetType":1,"viewCount":2096,"authorTweetTopStatus":1,"verified":2,"comments":[],"imageCount":0,"langContent":"EN","totalScore":0},{"id":620870264,"gmtCreate":1669690966159,"gmtModify":1676538224024,"author":{"id":"4130472326487360","authorId":"4130472326487360","name":"6f1a6f45","avatar":"https://static.laohu8.com/default-avatar.jpg","crmLevel":11,"crmLevelSwitch":0,"followedFlag":false,"idStr":"4130472326487360","authorIdStr":"4130472326487360"},"themes":[],"htmlText":"👍","listText":"👍","text":"👍","images":[],"top":1,"highlighted":1,"essential":1,"paper":1,"likeSize":0,"commentSize":0,"repostSize":0,"link":"https://ttm.financial/post/620870264","repostId":"2287453885","repostType":2,"isVote":1,"tweetType":1,"viewCount":1937,"authorTweetTopStatus":1,"verified":2,"comments":[],"imageCount":0,"langContent":"EN","totalScore":0},{"id":620870130,"gmtCreate":1669690916322,"gmtModify":1676538224016,"author":{"id":"4130472326487360","authorId":"4130472326487360","name":"6f1a6f45","avatar":"https://static.laohu8.com/default-avatar.jpg","crmLevel":11,"crmLevelSwitch":0,"followedFlag":false,"idStr":"4130472326487360","authorIdStr":"4130472326487360"},"themes":[],"htmlText":"👍","listText":"👍","text":"👍","images":[],"top":1,"highlighted":1,"essential":1,"paper":1,"likeSize":0,"commentSize":0,"repostSize":0,"link":"https://ttm.financial/post/620870130","repostId":"2287545465","repostType":2,"repost":{"id":"2287545465","kind":"news","pubTimestamp":1669681671,"share":"https://ttm.financial/m/news/2287545465?lang=en_US&edition=fundamental","pubTime":"2022-11-29 08:27","market":"us","language":"zh","title":"\"New Stock News\" 3D MEDICINES-B (01244. HK) will launch an IPO today, with a first-hand admission fee of 13,252.23 yuan","url":"https://stock-news.laohu8.com/highlight/detail?id=2287545465","media":"AAFN","summary":"生物医药公司3D MEDICINES-B公布招股详情，拟全球发售1,635万股，香港公开发售占一成，国际发售占九成。招股价介乎每股22.96至26.24元。每手500股计，一手入场费13,252.23元。该股今日起招股，下周三中午截止，预期将于12月15日挂牌。公司上市引入4名基石投资者，包括徐州经开区(香港)、Harvest、TradArt Investment SP及Mobilewise，合共认购2.35亿元公司股份。","content":"<p><html><body>The biopharmaceutical company 3D MEDICINES-B (01244. HK) announced the details of its IPO. It plans to sell 16.35 million shares globally, with Hong Kong public offering accounting for 10% and international offering accounting for 90%. The offering price ranges from 22.96 to 26.24 yuan per share. Each lot is 500 shares, and the admission fee for one lot is 13,252.23 yuan. The stock will be launched today (November 29th) and will close at noon next Wednesday (December 7th). It is expected to be listed on December 15th. The joint sponsors are CICC and<a href=\"https://laohu8.com/S/601066\">China Securities Investment</a>International. The company's listing introduced 4 cornerstone investors, including Xuzhou Economic Development Zone (Hong Kong), Harvest, TradArt Investment SP and Mobilewise, who subscribed for a total of 235 million yuan of company shares. For example, based on the median offering price of 24.6 yuan, the company's listing is expected to raise a net fund of about 245 million yuan, of which about 90% is mainly used for the research and development, regulatory filing and commercialization of products and drug candidates; About 10% will be used for general corporate and working capital purposes. (jl/w) ~ Aastock Financial News Website: www.aastocks.com</p><p></body></html></p>","source":"aastocks","collect":0,"html":"<!DOCTYPE html>\n<html>\n<head>\n<meta http-equiv=\"Content-Type\" content=\"text/html; charset=utf-8\" />\n<meta name=\"viewport\" content=\"width=device-width,initial-scale=1.0,minimum-scale=1.0,maximum-scale=1.0,user-scalable=no\"/>\n<meta name=\"format-detection\" content=\"telephone=no,email=no,address=no\" />\n<title>\"New Stock News\" 3D MEDICINES-B (01244. HK) will launch an IPO today, with a first-hand admission fee of 13,252.23 yuan</title>\n<style type=\"text/css\">\na,abbr,acronym,address,applet,article,aside,audio,b,big,blockquote,body,canvas,caption,center,cite,code,dd,del,details,dfn,div,dl,dt,\nem,embed,fieldset,figcaption,figure,footer,form,h1,h2,h3,h4,h5,h6,header,hgroup,html,i,iframe,img,ins,kbd,label,legend,li,mark,menu,nav,\nobject,ol,output,p,pre,q,ruby,s,samp,section,small,span,strike,strong,sub,summary,sup,table,tbody,td,tfoot,th,thead,time,tr,tt,u,ul,var,video{ font:inherit;margin:0;padding:0;vertical-align:baseline;border:0 }\nbody{ font-size:16px; line-height:1.5; color:#999; background:transparent; }\n.wrapper{ overflow:hidden;word-break:break-all;padding:10px; }\nh1,h2{ font-weight:normal; line-height:1.35; margin-bottom:.6em; }\nh3,h4,h5,h6{ line-height:1.35; margin-bottom:1em; }\nh1{ font-size:24px; }\nh2{ font-size:20px; }\nh3{ font-size:18px; }\nh4{ font-size:16px; }\nh5{ font-size:14px; }\nh6{ font-size:12px; }\np,ul,ol,blockquote,dl,table{ margin:1.2em 0; }\nul,ol{ margin-left:2em; }\nul{ list-style:disc; }\nol{ list-style:decimal; }\nli,li p{ margin:10px 0;}\nimg{ max-width:100%;display:block;margin:0 auto 1em; }\nblockquote{ color:#B5B2B1; border-left:3px solid #aaa; padding:1em; }\nstrong,b{font-weight:bold;}\nem,i{font-style:italic;}\ntable{ width:100%;border-collapse:collapse;border-spacing:1px;margin:1em 0;font-size:.9em; }\nth,td{ padding:5px;text-align:left;border:1px solid #aaa; }\nth{ font-weight:bold;background:#5d5d5d; }\n.symbol-link{font-weight:bold;}\n/* header{ border-bottom:1px solid #494756; } */\n.title{ margin:0 0 8px;line-height:1.3;color:#ddd; }\n.meta {color:#5e5c6d;font-size:13px;margin:0 0 .5em; }\na{text-decoration:none; color:#2a4b87;}\n.meta .head { display: inline-block; overflow: hidden}\n.head .h-thumb { width: 30px; height: 30px; margin: 0; padding: 0; border-radius: 50%; float: left;}\n.head .h-content { margin: 0; padding: 0 0 0 9px; float: left;}\n.head .h-name {font-size: 13px; color: #eee; margin: 0;}\n.head .h-time {font-size: 12.5px; color: #7E829C; margin: 0;}\n.small {font-size: 12.5px; display: inline-block; transform: scale(0.9); -webkit-transform: scale(0.9); transform-origin: left; -webkit-transform-origin: left;}\n.smaller {font-size: 12.5px; display: inline-block; transform: scale(0.8); -webkit-transform: scale(0.8); transform-origin: left; -webkit-transform-origin: left;}\n.bt-text {font-size: 12px;margin: 1.5em 0 0 0}\n.bt-text p {margin: 0}\n</style>\n</head>\n<body>\n<div class=\"wrapper\">\n<header>\n<h2 class=\"title\">\n\"New Stock News\" 3D MEDICINES-B (01244. HK) will launch an IPO today, with a first-hand admission fee of 13,252.23 yuan\n</h2>\n<h4 class=\"meta\">\n<p class=\"head\">\n<strong class=\"h-name small\">AAFN</strong><span class=\"h-time small\">2022-11-29 08:27</span>\n</p>\n</h4>\n</header>\n<article>\n<p><html><body>The biopharmaceutical company 3D MEDICINES-B (01244. HK) announced the details of its IPO. It plans to sell 16.35 million shares globally, with Hong Kong public offering accounting for 10% and international offering accounting for 90%. The offering price ranges from 22.96 to 26.24 yuan per share. Each lot is 500 shares, and the admission fee for one lot is 13,252.23 yuan. The stock will be launched today (November 29th) and will close at noon next Wednesday (December 7th). It is expected to be listed on December 15th. The joint sponsors are CICC and<a href=\"https://laohu8.com/S/601066\">China Securities Investment</a>International. The company's listing introduced 4 cornerstone investors, including Xuzhou Economic Development Zone (Hong Kong), Harvest, TradArt Investment SP and Mobilewise, who subscribed for a total of 235 million yuan of company shares. For example, based on the median offering price of 24.6 yuan, the company's listing is expected to raise a net fund of about 245 million yuan, of which about 90% is mainly used for the research and development, regulatory filing and commercialization of products and drug candidates; About 10% will be used for general corporate and working capital purposes. (jl/w) ~ Aastock Financial News Website: www.aastocks.com</p><p></body></html></p>\n<div class=\"bt-text\">\n\n\n<p> source：<a href=\"http://www.aastocks.com/apps/data/iphone/news/newscontent.aspx?newsid=NOW.1229684&style=5&chgstyle=1&categoryid=stock&width=320&market_id=hk&fontary=3&platform=iPhone&language=sc&isfirstreq=1&sourceid=aafn&datatype=0\">AAFN</a></p>\n\n\n</div>\n</article>\n</div>\n</body>\n</html>\n","type":0,"thumbnail":"","relate_stocks":{"LU0140636845.USD":"施罗德大中华区股票A Acc","LU0251144936.SGD":"Fidelity Sustainable Asia Equity A-SGD","LU0067412154.USD":"UBS (LUX) EQUITY FUND -  CHINA OPPORTUNITY \"P\" (USD) ACC","LU0501845795.SGD":"瑞银大中华区股票基金P Acc SGD","LU0043850808.USD":"HSBC GIF ASIA EX JAPAN EQUITY \"AD\" INC","LU0873338254.USD":"FULLERTON LUX FUNDS - ASIA GROWTH & INCOME EQUITIE \"I\" (USD) INC","LU0577902538.SGD":"Fullerton Lux Funds - Asia Growth and Income Equities A Acc SGD","BK1589":"北水核心资产","BK1521":"挪威政府全球养老基金持仓","LU0417516738.SGD":"Allianz Hong Kong Equity AT Acc SGD","LU0348735423.USD":"ALLIANZ HONG KONG EQUITY \"A\" (USD) INC","LU0577902611.USD":"FULLERTON LUX FUNDS - ASIA GROWTH & INCOME EQUITIE \"A\" (USD) ACC","SG9999004220.SGD":"Nikko AM Shenton Asia Dividend Equity Fund  SGD","LU0577902454.USD":"FULLERTON LUX FUNDS - ASIA GROWTH & INCOME EQUITIE \"I\" (USD) ACC","LU0577902371.SGD":"FULLERTON LUX FUNDS - ASIA GROWTH & INCOME EQUITIE \"I\" (SGD) ACC","BK1131":"金融交易所和数据","LU0456846285.SGD":"JPMorgan Funds - Greater China A (acc) SGD","01244":"思路迪医药股份","LU1044876610.USD":"THREADNEEDLE (LUX) ASIAN CONTRARIAN EQUITY \"ZU\" (USD) ACC","SG9999002463.SGD":"LionGlobal China Growth SGD","LU0072913022.USD":"UBS (LUX) EQUITY FUND -  GREATER CHINA \"P\" (USD) ACC","LU0048597586.USD":"富达亚洲焦点A","LU0572944931.SGD":"Janus Henderson Horizon China Opportunities A2 SGD","LU1226287529.USD":"UBS (LUX) KEY SELECTION SICAV - CHINA ALLOCATION  OPPORTUNITY (USD) \"P\" (USD) ACC","LU1642822792.SGD":"THREADNEEDLE (LUX) ASIAN CONTRARIAN EQUITY \"A\" (SGD) ACC","00388":"香港交易所","LU1044874839.SGD":"THREADNEEDLE (LUX) ASIAN CONTRARIAN EQUITY \"AGH\" (SGDHDG) ACC","LU0211977185.USD":"EASTSPRING INVESTMENTS GREATER CHINA EQUITY \"A\" ACC","LU2039709279.SGD":"MANULIFE GF DRAGON GROWTH \"AA\" (SGDHDG) INC","LU1044875133.USD":"天利亚洲反向股票 AU Acc","LU0327786744.USD":"Janus Henderson Horizon China Opportunities A2 USD","LU1807302812.USD":"UBS (LUX) EQUITY SICAV ALL CHINA \"P\" (USD) ACC","LU0577902298.EUR":"FULLERTON LUX FUNDS - ASIA GROWTH & INCOME EQUITIE \"I\" (EUR) ACC"},"source_url":"http://www.aastocks.com/apps/data/iphone/news/newscontent.aspx?newsid=NOW.1229684&style=5&chgstyle=1&categoryid=stock&width=320&market_id=hk&fontary=3&platform=iPhone&language=sc&isfirstreq=1&sourceid=aafn&datatype=0","is_english":false,"share_image_url":"https://static.laohu8.com/51f6b9126f36f92bbf92982596066e5a","article_id":"2287545465","content_text":"生物医药公司3D MEDICINES-B(01244.HK)公布招股详情，拟全球发售1,635万股，香港公开发售占一成，国际发售占九成。招股价介乎每股22.96至26.24元。每手500股计，一手入场费13,252.23元。该股今日(11月29日)起招股，下周三(12月7日)中午截止，预期将于12月15日挂牌。联席保荐人为中金及中信建投国际。公司上市引入4名基石投资者，包括徐州经开区(香港)、Harvest、TradArt Investment SP及Mobilewise，合共认购2.35亿元公司股份。如以招股价中位数24.6元计，公司上市料净集资约2.45亿元，当中约90%主要用于产品和候选药物的研发、监管备案及商业化；约10%将用于一般企业及营运资金用途。(jl/w)~阿思达克财经新闻网址: www.aastocks.com","news_type":1,"symbols_score_info":{"00388":0.9,"01244":1}},"isVote":1,"tweetType":1,"viewCount":1797,"authorTweetTopStatus":1,"verified":2,"comments":[],"imageCount":0,"langContent":"EN","totalScore":0},{"id":620870046,"gmtCreate":1669690798187,"gmtModify":1676538224000,"author":{"id":"4130472326487360","authorId":"4130472326487360","name":"6f1a6f45","avatar":"https://static.laohu8.com/default-avatar.jpg","crmLevel":11,"crmLevelSwitch":0,"followedFlag":false,"idStr":"4130472326487360","authorIdStr":"4130472326487360"},"themes":[],"htmlText":"👍","listText":"👍","text":"👍","images":[],"top":1,"highlighted":1,"essential":1,"paper":1,"likeSize":0,"commentSize":0,"repostSize":0,"link":"https://ttm.financial/post/620870046","repostId":"2287254564","repostType":2,"repost":{"id":"2287254564","kind":"highlight","weMediaInfo":{"introduction":"凤凰网港股","home_visible":1,"media_name":"凤凰网港股","id":"1002821290","head_image":"https://static.tigerbbs.com/b6fb647077f1ce46dc341fc35c26e817"},"pubTimestamp":1669681789,"share":"https://ttm.financial/m/news/2287254564?lang=en_US&edition=fundamental","pubTime":"2022-11-29 08:29","market":"us","language":"zh","title":"[New IPO] 3D MEDICINES-B (01244) IPO admission fee is HK $13,252.23 starting today","url":"https://stock-news.laohu8.com/highlight/detail?id=2287254564","media":"凤凰网港股","summary":"3D MEDICINES-B今起招股，拟全球发售1635万股，其中，香港发售占10%，国际发售占90%，另有超额配股权15%。每股发售价介乎22.96-26.24港元，每手500股，入场费13252.23港元；中金公司及中信建投国际为联席保荐人；该股份预期将于12月15日挂牌上市。据悉，3D MEDICINES是一家成立于2014年的生物医药公司，致力于为癌症患者，尤其是那些需要长期治疗的患者研发肿瘤药物。","content":"<p><html><body>3D MEDICINES-B (01244) will launch an IPO today and plans to sell 16.35 million shares globally, of which the Hong Kong offering accounts for 10%, the international offering accounts for 90%, and there is an over-allotment option of 15%. The offer price per share ranges from HK $22.96-HK $26.24, with 500 shares per lot, and the admission fee is HK $13,252.23;<a href=\"https://laohu8.com/S/601995\">CICC</a>(b)<a href=\"https://laohu8.com/S/601066\">China Securities Investment</a>International as a joint sponsor; The shares are expected to be listed on December 15. It is reported that 3D MEDICINES is a biomedical company established in 2014, dedicated to the development of oncology drugs for cancer patients, especially those who need long-term treatment. The company's core business model is to develop and commercialize oncology products and drug candidates through joint cooperative development, licensing introduction and independent discovery. A pipeline containing one core product and 11 drug candidates has been established, of which the core product envolimab (brand name: Enveda) is the pillar product, which has been approved in November 2021 and launched in December 2021 Commercialization, and 7 other drug candidates are in the clinical stage. Use of funds raised: About 90% will be mainly used for the research and development, regulatory filing and commercialization of the company's products and drug candidates; About 10% will be used for the company's general corporate and working capital purposes.</p><p></body></html></p>","collect":0,"html":"<!DOCTYPE html>\n<html>\n<head>\n<meta http-equiv=\"Content-Type\" content=\"text/html; charset=utf-8\" />\n<meta name=\"viewport\" content=\"width=device-width,initial-scale=1.0,minimum-scale=1.0,maximum-scale=1.0,user-scalable=no\"/>\n<meta name=\"format-detection\" content=\"telephone=no,email=no,address=no\" />\n<title>[New IPO] 3D MEDICINES-B (01244) IPO admission fee is HK $13,252.23 starting today</title>\n<style type=\"text/css\">\na,abbr,acronym,address,applet,article,aside,audio,b,big,blockquote,body,canvas,caption,center,cite,code,dd,del,details,dfn,div,dl,dt,\nem,embed,fieldset,figcaption,figure,footer,form,h1,h2,h3,h4,h5,h6,header,hgroup,html,i,iframe,img,ins,kbd,label,legend,li,mark,menu,nav,\nobject,ol,output,p,pre,q,ruby,s,samp,section,small,span,strike,strong,sub,summary,sup,table,tbody,td,tfoot,th,thead,time,tr,tt,u,ul,var,video{ font:inherit;margin:0;padding:0;vertical-align:baseline;border:0 }\nbody{ font-size:16px; line-height:1.5; color:#999; background:transparent; }\n.wrapper{ overflow:hidden;word-break:break-all;padding:10px; }\nh1,h2{ font-weight:normal; line-height:1.35; margin-bottom:.6em; }\nh3,h4,h5,h6{ line-height:1.35; margin-bottom:1em; }\nh1{ font-size:24px; }\nh2{ font-size:20px; }\nh3{ font-size:18px; }\nh4{ font-size:16px; }\nh5{ font-size:14px; }\nh6{ font-size:12px; }\np,ul,ol,blockquote,dl,table{ margin:1.2em 0; }\nul,ol{ margin-left:2em; }\nul{ list-style:disc; }\nol{ list-style:decimal; }\nli,li p{ margin:10px 0;}\nimg{ max-width:100%;display:block;margin:0 auto 1em; }\nblockquote{ color:#B5B2B1; border-left:3px solid #aaa; padding:1em; }\nstrong,b{font-weight:bold;}\nem,i{font-style:italic;}\ntable{ width:100%;border-collapse:collapse;border-spacing:1px;margin:1em 0;font-size:.9em; }\nth,td{ padding:5px;text-align:left;border:1px solid #aaa; }\nth{ font-weight:bold;background:#5d5d5d; }\n.symbol-link{font-weight:bold;}\n/* header{ border-bottom:1px solid #494756; } */\n.title{ margin:0 0 8px;line-height:1.3;color:#ddd; }\n.meta {color:#5e5c6d;font-size:13px;margin:0 0 .5em; }\na{text-decoration:none; color:#2a4b87;}\n.meta .head { display: inline-block; overflow: hidden}\n.head .h-thumb { width: 30px; height: 30px; margin: 0; padding: 0; border-radius: 50%; float: left;}\n.head .h-content { margin: 0; padding: 0 0 0 9px; float: left;}\n.head .h-name {font-size: 13px; color: #eee; margin: 0;}\n.head .h-time {font-size: 12.5px; color: #7E829C; margin: 0;}\n.small {font-size: 12.5px; display: inline-block; transform: scale(0.9); -webkit-transform: scale(0.9); transform-origin: left; -webkit-transform-origin: left;}\n.smaller {font-size: 12.5px; display: inline-block; transform: scale(0.8); -webkit-transform: scale(0.8); transform-origin: left; -webkit-transform-origin: left;}\n.bt-text {font-size: 12px;margin: 1.5em 0 0 0}\n.bt-text p {margin: 0}\n</style>\n</head>\n<body>\n<div class=\"wrapper\">\n<header>\n<h2 class=\"title\">\n[New IPO] 3D MEDICINES-B (01244) IPO admission fee is HK $13,252.23 starting today\n</h2>\n<h4 class=\"meta\">\n<a class=\"head\" href=\"https://laohu8.com/wemedia/1002821290\">\n\n<div class=\"h-thumb\" style=\"background-image:url(https://static.tigerbbs.com/b6fb647077f1ce46dc341fc35c26e817);background-size:cover;\"></div>\n\n<div class=\"h-content\">\n<p class=\"h-name\">凤凰网港股 </p>\n<p class=\"h-time smaller\">2022-11-29 08:29</p>\n</div>\n</a>\n</h4>\n</header>\n<article>\n<p><html><body>3D MEDICINES-B (01244) will launch an IPO today and plans to sell 16.35 million shares globally, of which the Hong Kong offering accounts for 10%, the international offering accounts for 90%, and there is an over-allotment option of 15%. The offer price per share ranges from HK $22.96-HK $26.24, with 500 shares per lot, and the admission fee is HK $13,252.23;<a href=\"https://laohu8.com/S/601995\">CICC</a>(b)<a href=\"https://laohu8.com/S/601066\">China Securities Investment</a>International as a joint sponsor; The shares are expected to be listed on December 15. It is reported that 3D MEDICINES is a biomedical company established in 2014, dedicated to the development of oncology drugs for cancer patients, especially those who need long-term treatment. The company's core business model is to develop and commercialize oncology products and drug candidates through joint cooperative development, licensing introduction and independent discovery. A pipeline containing one core product and 11 drug candidates has been established, of which the core product envolimab (brand name: Enveda) is the pillar product, which has been approved in November 2021 and launched in December 2021 Commercialization, and 7 other drug candidates are in the clinical stage. Use of funds raised: About 90% will be mainly used for the research and development, regulatory filing and commercialization of the company's products and drug candidates; About 10% will be used for the company's general corporate and working capital purposes.</p><p></body></html></p>\n</article>\n</div>\n</body>\n</html>\n","type":0,"thumbnail":"","relate_stocks":{"01244":"思路迪医药股份","IPO":"Renaissance IPO ETF"},"source_url":"http://hknews.szfuit.com/newRssInfo/feed?original_id=62a79e0fe0fe0a2c4d3a7e8494242b53","is_english":false,"share_image_url":"https://static.laohu8.com/e9f99090a1c2ed51c021029395664489","article_id":"2287254564","content_text":"3D MEDICINES-B(01244)今起招股，拟全球发售1635万股，其中，香港发售占10%，国际发售占90%，另有超额配股权15%。每股发售价介乎22.96-26.24港元，每手500股，入场费13252.23港元；中金公司及中信建投国际为联席保荐人；该股份预期将于12月15日挂牌上市。据悉，3D MEDICINES是一家成立于2014年的生物医药公司，致力于为癌症患者，尤其是那些需要长期治疗的患者研发肿瘤药物。公司的核心业务模式是通过联合合作开发、许可引进及自主发现等方式，开发及商业化肿瘤产品及候选药物。已建立一条包含一款核心产品及11款候选药物的管线，其中核心产品恩沃利单抗(品牌名:恩维达)为支柱产品，已于2021年11月获批并于2021年12月商业化，另有7款其他候选药物处于 临床阶段。 所筹资金用途：约90%将主要用于公司产品和候选药物的研发、监管备案及商业化；约10%将用于公司的一般企业及营运资金用途。","news_type":1,"symbols_score_info":{"IPO":1,"01244":1}},"isVote":1,"tweetType":1,"viewCount":2380,"authorTweetTopStatus":1,"verified":2,"comments":[],"imageCount":0,"langContent":"EN","totalScore":0},{"id":620847528,"gmtCreate":1669690625866,"gmtModify":1676538223984,"author":{"id":"4130472326487360","authorId":"4130472326487360","name":"6f1a6f45","avatar":"https://static.laohu8.com/default-avatar.jpg","crmLevel":11,"crmLevelSwitch":0,"followedFlag":false,"idStr":"4130472326487360","authorIdStr":"4130472326487360"},"themes":[],"htmlText":"👍","listText":"👍","text":"👍","images":[],"top":1,"highlighted":1,"essential":1,"paper":1,"likeSize":0,"commentSize":0,"repostSize":0,"link":"https://ttm.financial/post/620847528","repostId":"1107729224","repostType":2,"repost":{"id":"1107729224","kind":"news","weMediaInfo":{"introduction":"为用户提供金融资讯、行情、数据，旨在帮助投资者理解世界，做投资决策。","home_visible":1,"media_name":"老虎资讯综合","id":"102","head_image":"https://static.tigerbbs.com/8274c5b9d4c2852bfb1c4d6ce16c68ba"},"pubTimestamp":1669684496,"share":"https://ttm.financial/m/news/1107729224?lang=en_US&edition=fundamental","pubTime":"2022-11-29 09:14","market":"hk","language":"zh","title":"New Stock Offering | 3D MEDICINES-B offers IPO today, admission fee is HK $13,252.23","url":"https://stock-news.laohu8.com/highlight/detail?id=1107729224","media":"老虎资讯综合","summary":"11月29日，3D MEDICINES-B发布公告，公司拟全球发售1635万股股份，其中中国香港发售股份163.5万股，国际发售股份1471.5万股，另有15%超额配股权；2022年11月29日至12","content":"<p><html><head></head><body>November 29th,<a href=\"https://laohu8.com/S/01244\">3D MEDICINES-B</a>Announced that the company plans to sell 16.35 million shares globally, including 1.635 million shares offered in Hong Kong, China, 14.715 million shares offered internationally, and a 15% over-allotment option; The IPO will be held from November 29 to December 7, 2022, and the expected pricing date is December 7; The offer price will be HK $22.96-26.24 per offer share, with 500 shares per lot, and the admission fee will be approximately HK $13,252.23; CICC and China Securities International are joint sponsors; It is expected that the Shares will be listed on the Main Board of the Stock Exchange on 15 December 2022.</p><p><img src=\"https://static.tigerbbs.com/2c0be958a118bf20d9cd87db8c523bd9\" tg-width=\"897\" tg-height=\"709\" width=\"100%\" height=\"auto\"/></p><p><b>Subscription ladder:</b></p><p>There are 500 shares per lot, and the admission fee is HK $13,252.23.</p><p>The threshold for Group B is 2 million shares, and the funds required for subscription are approximately HK $5,300,891.97.</p><p><img src=\"https://static.tigerbbs.com/c92f15f2d5dc92f088705e284d6c494f\" tg-width=\"897\" tg-height=\"535\" width=\"100%\" height=\"auto\"/></p><p>The Group is a biomedical company founded in 2014, dedicated to the development of oncology drugs for cancer patients, especially those who need long-term treatment. The Group's core business model is to develop and commercialize oncology products and drug candidates through joint cooperation development, licensing introduction and independent discovery. The Group plans to further enhance the Group's internal discovery capabilities after listing and continue to use the cooperative development and licensing introduction model to carry out clinical trials for more indications for the benefit of chronic cancer patients. As of the Latest Practicable Date, the Group has established a pipeline consisting of one core product and 11 drug candidates, of which the core product envolimab (brand name: Envida ® ) is the pillar product of the Group, which has been approved in November 2021 and commercialized in December 2021, and seven other drug candidates are in the clinical stage (including that the Group has initiated clinical trials or has obtained IND approval and is preparing to initiate clinical trial drug candidates).</p><p>The Group's core product, envolimab, is a subcutaneous PD-L1 antibody, which has been approved in China for the treatment of previously treated microsatellite high instability (MSI-H)/mismatch repair function defect (dMMR) advanced solid tumors. As of the Latest Practicable Date, the Group's core products were only approved for this indication. According to Frost & Sullivan, as of the Latest Practicable Date, there were four commercial peers and five clinical-stage peers competing with the Core Products in China for the treatment of MSI-H/dMMR tumors. The Group faces fierce competition from existing products and potential drug candidates (including monoclonal and bispecific antibodies targeting PD-1/L1) in the overall oncology market. The market opportunity for core products may be small because it targets most Late-stage treatment of target indications. For example, the incidence of MSI-H/dMMR advanced solid tumors in China was approximately 146,100 cases in 2021 and is expected to reach approximately 186,000 cases in 2030, and only approximately 50% of cases will receive more than one treatment.</p><p>The Group has entered into a cornerstone investment agreement, pursuant to which the cornerstone investors have agreed to subscribe for an aggregate of HK $235 million in Offer Shares at the Offer Price subject to certain conditions. Assuming an Offer Price of HK $24.60 (i.e. the mid-point of the indicative Offer Price range set out in this prospectus), the total number of Offer Shares to be subscribed for by cornerstone investors is 9,536,500 Offer Shares. Cornerstone investors include Xuzhou Economic and Technological Development Zone (Hong Kong) Investment Co., Ltd., Harvest, TradArt Investment SP, and Mobilewise.</p><p><img src=\"https://static.tigerbbs.com/65b7af483bb5bb129e17cb7a66844666\" tg-width=\"894\" tg-height=\"522\" width=\"100%\" height=\"auto\"/></p><p>Assuming that the over-allotment option is not exercised and the offer price is HK $24.60 per share, the Group estimates that the total net proceeds from the global offering that the company will receive will be approximately HK $245 million. The Group currently plans to use approximately 90% of the net proceeds that the Group will receive from this offering mainly for the research and development, regulatory filing and commercialization of the Group's products and drug candidates; And approximately 10% will be used for the group's general corporate and working capital purposes.</p><p></body></html></p>","collect":0,"html":"<!DOCTYPE html>\n<html>\n<head>\n<meta http-equiv=\"Content-Type\" content=\"text/html; charset=utf-8\" />\n<meta name=\"viewport\" content=\"width=device-width,initial-scale=1.0,minimum-scale=1.0,maximum-scale=1.0,user-scalable=no\"/>\n<meta name=\"format-detection\" content=\"telephone=no,email=no,address=no\" />\n<title>New Stock Offering | 3D MEDICINES-B offers IPO today, admission fee is HK $13,252.23</title>\n<style type=\"text/css\">\na,abbr,acronym,address,applet,article,aside,audio,b,big,blockquote,body,canvas,caption,center,cite,code,dd,del,details,dfn,div,dl,dt,\nem,embed,fieldset,figcaption,figure,footer,form,h1,h2,h3,h4,h5,h6,header,hgroup,html,i,iframe,img,ins,kbd,label,legend,li,mark,menu,nav,\nobject,ol,output,p,pre,q,ruby,s,samp,section,small,span,strike,strong,sub,summary,sup,table,tbody,td,tfoot,th,thead,time,tr,tt,u,ul,var,video{ font:inherit;margin:0;padding:0;vertical-align:baseline;border:0 }\nbody{ font-size:16px; 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}\n.meta {color:#5e5c6d;font-size:13px;margin:0 0 .5em; }\na{text-decoration:none; color:#2a4b87;}\n.meta .head { display: inline-block; overflow: hidden}\n.head .h-thumb { width: 30px; height: 30px; margin: 0; padding: 0; border-radius: 50%; float: left;}\n.head .h-content { margin: 0; padding: 0 0 0 9px; float: left;}\n.head .h-name {font-size: 13px; color: #eee; margin: 0;}\n.head .h-time {font-size: 12.5px; color: #7E829C; margin: 0;}\n.small {font-size: 12.5px; display: inline-block; transform: scale(0.9); -webkit-transform: scale(0.9); transform-origin: left; -webkit-transform-origin: left;}\n.smaller {font-size: 12.5px; display: inline-block; transform: scale(0.8); -webkit-transform: scale(0.8); transform-origin: left; -webkit-transform-origin: left;}\n.bt-text {font-size: 12px;margin: 1.5em 0 0 0}\n.bt-text p {margin: 0}\n</style>\n</head>\n<body>\n<div class=\"wrapper\">\n<header>\n<h2 class=\"title\">\nNew Stock Offering | 3D MEDICINES-B offers IPO today, admission fee is HK $13,252.23\n</h2>\n<h4 class=\"meta\">\n<a class=\"head\" href=\"https://laohu8.com/wemedia/102\">\n\n<div class=\"h-thumb\" style=\"background-image:url(https://static.tigerbbs.com/8274c5b9d4c2852bfb1c4d6ce16c68ba);background-size:cover;\"></div>\n\n<div class=\"h-content\">\n<p class=\"h-name\">老虎资讯综合 </p>\n<p class=\"h-time smaller\">2022-11-29 09:14</p>\n</div>\n</a>\n</h4>\n</header>\n<article>\n<p><html><head></head><body>November 29th,<a href=\"https://laohu8.com/S/01244\">3D MEDICINES-B</a>Announced that the company plans to sell 16.35 million shares globally, including 1.635 million shares offered in Hong Kong, China, 14.715 million shares offered internationally, and a 15% over-allotment option; The IPO will be held from November 29 to December 7, 2022, and the expected pricing date is December 7; The offer price will be HK $22.96-26.24 per offer share, with 500 shares per lot, and the admission fee will be approximately HK $13,252.23; CICC and China Securities International are joint sponsors; It is expected that the Shares will be listed on the Main Board of the Stock Exchange on 15 December 2022.</p><p><img src=\"https://static.tigerbbs.com/2c0be958a118bf20d9cd87db8c523bd9\" tg-width=\"897\" tg-height=\"709\" width=\"100%\" height=\"auto\"/></p><p><b>Subscription ladder:</b></p><p>There are 500 shares per lot, and the admission fee is HK $13,252.23.</p><p>The threshold for Group B is 2 million shares, and the funds required for subscription are approximately HK $5,300,891.97.</p><p><img src=\"https://static.tigerbbs.com/c92f15f2d5dc92f088705e284d6c494f\" tg-width=\"897\" tg-height=\"535\" width=\"100%\" height=\"auto\"/></p><p>The Group is a biomedical company founded in 2014, dedicated to the development of oncology drugs for cancer patients, especially those who need long-term treatment. The Group's core business model is to develop and commercialize oncology products and drug candidates through joint cooperation development, licensing introduction and independent discovery. The Group plans to further enhance the Group's internal discovery capabilities after listing and continue to use the cooperative development and licensing introduction model to carry out clinical trials for more indications for the benefit of chronic cancer patients. As of the Latest Practicable Date, the Group has established a pipeline consisting of one core product and 11 drug candidates, of which the core product envolimab (brand name: Envida ® ) is the pillar product of the Group, which has been approved in November 2021 and commercialized in December 2021, and seven other drug candidates are in the clinical stage (including that the Group has initiated clinical trials or has obtained IND approval and is preparing to initiate clinical trial drug candidates).</p><p>The Group's core product, envolimab, is a subcutaneous PD-L1 antibody, which has been approved in China for the treatment of previously treated microsatellite high instability (MSI-H)/mismatch repair function defect (dMMR) advanced solid tumors. As of the Latest Practicable Date, the Group's core products were only approved for this indication. According to Frost & Sullivan, as of the Latest Practicable Date, there were four commercial peers and five clinical-stage peers competing with the Core Products in China for the treatment of MSI-H/dMMR tumors. The Group faces fierce competition from existing products and potential drug candidates (including monoclonal and bispecific antibodies targeting PD-1/L1) in the overall oncology market. The market opportunity for core products may be small because it targets most Late-stage treatment of target indications. For example, the incidence of MSI-H/dMMR advanced solid tumors in China was approximately 146,100 cases in 2021 and is expected to reach approximately 186,000 cases in 2030, and only approximately 50% of cases will receive more than one treatment.</p><p>The Group has entered into a cornerstone investment agreement, pursuant to which the cornerstone investors have agreed to subscribe for an aggregate of HK $235 million in Offer Shares at the Offer Price subject to certain conditions. Assuming an Offer Price of HK $24.60 (i.e. the mid-point of the indicative Offer Price range set out in this prospectus), the total number of Offer Shares to be subscribed for by cornerstone investors is 9,536,500 Offer Shares. Cornerstone investors include Xuzhou Economic and Technological Development Zone (Hong Kong) Investment Co., Ltd., Harvest, TradArt Investment SP, and Mobilewise.</p><p><img src=\"https://static.tigerbbs.com/65b7af483bb5bb129e17cb7a66844666\" tg-width=\"894\" tg-height=\"522\" width=\"100%\" height=\"auto\"/></p><p>Assuming that the over-allotment option is not exercised and the offer price is HK $24.60 per share, the Group estimates that the total net proceeds from the global offering that the company will receive will be approximately HK $245 million. The Group currently plans to use approximately 90% of the net proceeds that the Group will receive from this offering mainly for the research and development, regulatory filing and commercialization of the Group's products and drug candidates; And approximately 10% will be used for the group's general corporate and working capital purposes.</p><p></body></html></p>\n</article>\n</div>\n</body>\n</html>\n","type":0,"thumbnail":"https://static.tigerbbs.com/26d35a88c8d9d9d46abd395d2bd24396","relate_stocks":{"01244":"思路迪医药股份"},"source_url":"","is_english":false,"share_image_url":"https://static.laohu8.com/e9f99090a1c2ed51c021029395664489","article_id":"1107729224","content_text":"11月29日，3D MEDICINES-B发布公告，公司拟全球发售1635万股股份，其中中国香港发售股份163.5万股，国际发售股份1471.5万股，另有15%超额配股权；2022年11月29日至12月7日招股，预期定价日为12月7日；发售价将为每股发售股份22.96-26.24港元，每手买卖单位500股，入场费约13252.23港元；中金公司及中信建投国际为联席保荐人；预期股份将于2022年12月15日于联交所主板挂牌上市。申购阶梯：每手500股，入场费13252.23港元。乙组门槛为200000万股，申购所需资金约5300891.97港元。集团是一家成立于2014年的生物医药公司，致力于为癌症患者，尤其是那些需要长期治疗的患者研发肿瘤药物。集团的核心业务模式是通过联合合作开发、许可引进及自主发现等方式，开发及商业化肿瘤产品及候选药物。集团计划于上市后进一步提升集团的内部发现能力及继续利用合作开发及许可引进模式开展针对更多适应症的临床试验造福慢性癌症患者。截至最后实际可行日期，集团已建立一条包含一款核心产品及11款候选药物的管线，其中核心产品恩沃利单抗(品牌名：恩维达®)为集团的支柱产品，已于2021年11月获批并于2021年12月商业化，另有七款其他候选药物处于临床阶段(包括集团已启动临床试验或已取得IND批准及正准备启动临床试验的候选药物)。集团的核心产品恩沃利单抗是一款皮下注射PD-L1抗体，其已在中国获批用于治疗既往接受过治疗的微卫星高度不稳定(MSI-H)╱错配修复功能缺陷(dMMR)晚期实体瘤。截至最后实际可行日期，集团的核心产品仅获批用于这一适应症。根据弗若斯特沙利文的资料，截至最后实际可行日期，在中国有四名商业化同行及五名临床阶段同行就治疗MSI-H/dMMR肿瘤与核心产品竞争。集团于整个肿瘤市场面临来自现有产品及潜在候选药物(包括靶向PD-1/L1的单克隆及双特异性抗体)的激烈竞争，核心产品的市场机会可能很小，因为其靶向大多数目标适应症的晚期治疗。例如，MSI-H/ 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