The Big 5--AI x Biology, Financial Revolution, Commodities, Optics& The Power Bottleneck
The Big 5
1. AI x Biology:
$Tempus AI(TEM)$: The data layer
$CRISPR Therapeutics AG(CRSP)$: The execution layer cutting DNA at a specific site.
$Beam Therapeutics, Inc.(BEAM)$: Higher risk play on editing individual bases
$Recursion Pharmaceuticals, Inc.(RXRX)$: Data generation layer
$Eli Lilly(LLY)$: The entire stack
2. Financial Revolution:
$Coinbase Global, Inc.(COIN)$: The everthing crypto play
$Robinhood(HOOD)$: The distribution layer
$Securitize(SECZ)$: The purest tokenization play
3. Commodities:
Copper: $Global X Copper Miners ETF(COPX)$ $Trilogy Metals(TMQ)$
Solar: $Shoals Technologies Group(SHLS)$ $Invesco Solar ETF(TAN)$$Nextpower(NXT)$
Silver: $Contango Ore, Inc.(CTGO)$$iShares Silver Trust(SLV)$ $Hecla Mining(HL)$
Scandium: $Sunrise Energy Metals Ltd.(SREMF)$
4. Optics:
$Marvell Technology(MRVL)$: Just forecasted a 10x ramp up in revenue to 2031.
$Applied Optoelectronics(AAOI)$: Trades ~1.7x FY28 base case (131% CAGR).
$Himax(HIMX)$: Guiding to $100M in CPO revenue in FY26 with a big ramp up in 2027-2028
5. The Power Bottleneck:
$Bloom Energy Corp(BE)$: MS estimates Bloom will be the answer to ~20% of the US's data center power generation shortfall.
$Constellation Energy Corp(CEG)$: Owns the largest US nuclear fleet with huge hyperscaler deals
$Shoals Technologies Group(SHLS)$: A higher risk play on solar (electrical components)
$NuScale Power(SMR)$: A very long term and a very high risk play on the Small Modular Reactor market.
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